Cytokines in infectious diseases
نویسنده
چکیده
Interest in cytokines in infection is increasing exponentially both because of the central role these peptide molecules have in immune responses in a wide spectrum of human responses in health and disease1 and because they are likely to be pivotal in the development of new therapies and vaccine strategies. Immunity to infections and attempts by pathogens to avoid the host defence system provide some of the most elegant insights into the multitude of cytokine functions. This review is an update of some of the more recent developments in cytokine biology. It will not cover all aspects of cytokines in infection, but rather illustrate general principles, using examples found in infectious diseases of major pathogenic significance, and indicate how knowledge is being transferred to the clinic . The areas considered are:
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